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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Multivesicular body subunit 12A

UniprotKB/SwissProt ID: Q6P777 (Q6P777)

Gene Name: Mvb12a

Organism: Rattus norvegicus (Rat)

Function: Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in the ligand-mediated internalization and down-regulation of EGF receptor (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Nucleus. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Late endosome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR023341 MABP
IPR040335 MVB12A
IPR018798 MVB12A/B
IPR023340 UMA

The S-nitrosylation sites of Q6P777

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 229 TLHPRFEGKS C GPLNLSAFGD