Protein Name:
U5 small nuclear ribonucleoprotein 200 kDa helicase
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UniprotKB/SwissProt ID: Q6P4T2 (Q6P4T2)
Gene Name:
Snrnp200
Organism: Mus musculus (Mouse)
Function: Catalyzes the ATP-dependent unwinding of U4/U6 RNA duplices, an essential step in the assembly of a catalytically active spliceosome. Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity). Involved in spliceosome assembly, activation and disassembly. Mediates changes in the dynamic network of RNA-RNA interactions in the spliceosome
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6P4T2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
133 |
ALGDQPRDIL C GAADEVLAVL |
CCCCCHHHHH E EECCCCCEEE |
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20925432
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| 2 |
1580 |
RLTAIDILTT C AADIQRQRFL |
CCCCCHHHHH E EECCCCCEEE |
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| 3 |
428 |
QGSHFMANKR C QLPDGSFRRQ |
CCCCCHHHHH E EECCCCCEEE |
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20925432
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