Protein Name:
Endoplasmic reticulum aminopeptidase 2
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UniprotKB/SwissProt ID: Q6P179 (Q6P179)
Gene Name:
ERAP2
Organism: Homo sapiens (Human)
Function: Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane
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Graphical Visualization of S-nitrosylation Sites:
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