Protein Name:
Tropomyosin alpha-4 chain
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UniprotKB/SwissProt ID: Q6IRU2 (Q6IRU2)
Gene Name:
Tpm4
Organism: Mus musculus (Mouse)
Function: Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. Binds calcium (By similarity). Plays a role in platelet biogenesis (PubMed:28134622)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6IRU2
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
154 |
EERAEVSELK C GDLEEELKNV |
CCCHHHHHHH H HHHHHHHHHH |
8.84% |
20925432
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