Protein Name:
G-protein-signaling modulator 1
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UniprotKB/SwissProt ID: Q6IR34 (Q6IR34)
Gene Name:
Gpsm1
Organism: Mus musculus (Mouse)
Function: Guanine nucleotide dissociation inhibitor (GDI) which functions as a receptor-independent activator of heterotrimeric G-protein signaling. Keeps G(i/o) alpha subunit in its GDP-bound form thus uncoupling heterotrimeric G-proteins signaling from G protein-coupled receptors. Controls spindle orientation and asymmetric cell fate of cerebral cortical progenitors. May also be involved in macroautophagy in intestinal cells. May play a role in drug addiction
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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