Protein Name:
Ras-related protein Rab-12
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UniprotKB/SwissProt ID: Q6IQ22 (Q6IQ22)
Gene Name:
RAB12
Organism: Homo sapiens (Human)
Function: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB12 may play a role in protein transport from recycling endosomes to lysosomes regulating, for instance, the degradation of the transferrin receptor. Involved in autophagy (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Recycling endosome membrane. Lysosome membrane. Golgi apparatus membrane. Cytoplasmic vesicle, autophagosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6IQ22
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
183 |
FAQQITGMRF C EASAKDNFNV |
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