Protein Name:
Twinfilin-2
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UniprotKB/SwissProt ID: Q6IBS0 (Q6IBS0)
Gene Name:
TWF2
Organism: Homo sapiens (Human)
Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cytoplasm, perinuclear region. Cell projection, stereocilium
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6IBS0
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
141 |
FAGYQKHLSS C AAPAPLTSAE |
CCCCCCCCCC H HHHHHHHHHH |
3.17% |
2212679
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| 2 |
275 |
SIKERMLYSS C KSRLLDSVEQ |
CCCCCCCCCC H HHHHHHHHHH |
3.69% |
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| 3 |
67 |
VLPLLDAQQP C YLLYRLDSQN |
CCCCCCCCCC H HHHHHHHHHH |
3.04% |
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