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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Nucleoredoxin

UniprotKB/SwissProt ID: Q6DKJ4 (Q6DKJ4)

Gene Name: NXN

Organism: Homo sapiens (Human)

Function: Functions as a redox-dependent negative regulator of the Wnt signaling pathway, possibly by preventing ubiquitination of DVL3 by the BCR(KLHL12) complex. May also function as a transcriptional regulator act as a regulator of protein phosphatase 2A (PP2A) (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR041861 NRX_PDI_b
IPR012336 Thioredoxin-like_fold
IPR036249 Thioredoxin-like_sf
IPR013766 Thioredoxin_domain
IPR045870 TryX_NRX_thioredoxin_dom

The S-nitrosylation sites of Q6DKJ4

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 302 GRVEVLNDED C REFPWHPKPV