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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ubiquitin-fold modifier-conjugating enzyme 1

UniprotKB/SwissProt ID: Q6BBI8 (Q6BBI8)

Gene Name: Ufc1

Organism: Rattus norvegicus (Rat)

Function: E2-like enzyme which specifically catalyzes the second step in ufmylation. Accepts the ubiquitin-like modifier UFM1 from the E1 enzyme UBA5 and forms an intermediate with UFM1 via a thioester linkage. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, interferon response or reticulophagy (also called ER-phagy)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR016135 UBQ-conjugating_enzyme/RWD
IPR014806 Ufc1

The S-nitrosylation sites of Q6BBI8

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 69 NKEGTRWFGK C WYIHDFLKYE