Protein Name:
Pyrroline-5-carboxylate reductase 2
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UniprotKB/SwissProt ID: Q6AY23 (Q6AY23)
Gene Name:
Pycr2
Organism: Rattus norvegicus (Rat)
Function: Oxidoreductase that catalyzes the last step in proline biosynthesis, which corresponds to the reduction of pyrroline-5-carboxylate to L-proline using NAD(P)H. At physiologic concentrations, has higher specific activity in the presence of NADH. Involved in cellular response to oxidative stress. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Mitochondrion
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q6AY23
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
120 |
AFQPAPKVIR C MTNTPVVVRE |
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| 2 |
95 |
DVQERHIVVS C AAGVTISSVE |
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