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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cell division cycle 5-like protein

UniprotKB/SwissProt ID: Q6A068 (Q6A068)

Gene Name: Cdc5l

Organism: Mus musculus (Mouse)

Function: DNA-binding protein involved in cell cycle control. May act as a transcription activator. Plays a role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR). As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Nucleus speckle. Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR047242 CDC5L/Cef1
IPR021786 Cdc5p/Cef1_C
IPR009057 Homeodomain-like_sf
IPR017930 Myb_dom
IPR001005 SANT/Myb
IPR047240 SANT_CDC5L_II

The S-nitrosylation sites of Q6A068

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 769 EDSAIPRRLE C LKEDVQRQQE  CCCEEEECCC C CCCHHHHHHH  8.55% 21278135