Protein Name:
E3 ubiquitin-protein ligase listerin
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UniprotKB/SwissProt ID: Q6A009 (Q6A009)
Gene Name:
Ltn1
Organism: Mus musculus (Mouse)
Function: E3 ubiquitin-protein ligase (PubMed:19196968). component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation (By similarity). Within the RQC complex, LTN1 is recruited to stalled 60S ribosomal subunits by NEMF and mediates ubiquitination of stalled nascent chains (By similarity). Ubiquitination leads to VCP/p97 recruitment for extraction and degradation of the incomplete translation product (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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