\
logo
  Home | Contact us | Browse | Quick Search by UniProtKB ID, Keyword, PDBID

Menu:

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Read more...


Protein Name: Methionine--tRNA ligase, cytoplasmic
UniprotKB/SwissProt ID: Q68FL6 (Q68FL6)

Gene Name: Mars1

Organism: Mus musculus (Mouse)

Function: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Plays a role in the synthesis of ribosomal RNA in the nucleolus

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytosol. Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001412 aa-tRNA-synth_I_CS
IPR041872 Anticodon_Met
IPR010987 Glutathione-S-Trfase_C-like
IPR036282 Glutathione-S-Trfase_C_sf
IPR004046 GST_C
IPR041598 MARS_N
IPR023458 Met-tRNA_ligase_1
IPR014758 Met-tRNA_synth
IPR015413 Methionyl/Leucyl_tRNA_Synth
IPR033911 MetRS_core
IPR029038 MetRS_Zn
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
IPR009068 uS15_NS1_RNA-bd_sf
IPR000738 WHEP-TRS_dom
The S-nitrosylation sites of Q68FL6
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 407 FLADRFVEGV C PFCGYEEARG  CCEEECCCCC C CHHHHHHHHH  2.92%
2 568 NVPFHGLVFP C SVLGAEDNYT  CCEEECCCCC C CHHHHHHHHH  2.74%
3 789 ACRILATSFI C TLPAGHRIGT  CCEEECCCCC C CHHHHHHHHH  2.77% 22178444