Protein Name:
E3 SUMO-protein ligase SIZ1
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UniprotKB/SwissProt ID: Q680Q4 (Q680Q4)
Gene Name:
SIZ1
Organism: Arabidopsis thaliana (Mouse-ear cress)
Function: E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses (PubMed:15894620). Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugation and facilitates basal thermotolerance. Involved in freezing tolerance by mediating sumoylation of ICE1, a transcription activator of the cold signaling regulator CBF3/DREB1A. Acts as a positive regulator of drought stress tolerance. Acts as a floral repressor that promotes FLC expression by repressing FLD activity through sumoylation. Acts as a negative regulator of abscisic acid (ABA) signaling through ABI5 sumoylation. Mediates sumoylation of SCE1, GTE3 and GTE5. Functions as a negative regulator of SnRK1 signaling through sumoylation of several components of the SnRK1 complex (PubMed:26662259)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus speckle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q680Q4
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
430 |
FNRITSKMKH C DEEVTEIEVK |
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