UniprotKB/SwissProt ID: Q66T62 (Q66T62)
Gene Name:
G
Organism: Rabies virus (strain silver-haired bat-associated) (RABV)
Function: Attaches the virus to host cellular receptor, inducing endocytosis of the virion by using different host proteins including TFRC, GRM2 and ITGB1 (By similarity). In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Virion membrane
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