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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Trifunctional purine biosynthetic protein adenosine-3
UniprotKB/SwissProt ID: Q64737 (Q64737)

Gene Name: Gart

Organism: Mus musculus (Mouse)

Function: Trifunctional enzyme that catalyzes three distinct reactions as part of the 'de novo' inosine monophosphate biosynthetic pathway

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR002376 Formyl_transf_N
IPR036477 Formyl_transf_N_sf
IPR004607 GART
IPR001555 GART_AS
IPR016185 PreATP-grasp_dom_sf
IPR020561 PRibGlycinamid_synth_ATP-grasp
IPR000115 PRibGlycinamide_synth
IPR020560 PRibGlycinamide_synth_C-dom
IPR037123 PRibGlycinamide_synth_C_sf
IPR020559 PRibGlycinamide_synth_CS
IPR020562 PRibGlycinamide_synth_N
IPR010918 PurM-like_C_dom
IPR036676 PurM-like_C_sf
IPR016188 PurM-like_N
IPR036921 PurM-like_N_sf
IPR004733 PurM_cligase
IPR011054 Rudment_hybrid_motif
The S-nitrosylation sites of Q64737
No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 134 WRAFTNPEDA C SFITSANFPA  CCEEEEEECC C CHHHHHHHHH  5.44% 21278135
2 237 GPNTGGMGAY C PAPQVSKDLL  CCEEEEEECC C CHHHHHHHHH  1.99% 21278135
3 298 EFNCRFGDPE C QVILPLLKSD  CCEEEEEECC C CHHHHHHHHH  4.82% 21278135
4 646 LQYSSPAPGG C GDQTLGDLLL  CCEEEEEECC C CHHHHHHHHH  7.23%
5 93 VGDLTSAGVR C FGPTAQAAQL  CCEEEEEECC C CHHHHHHHHH  4.26% 21278135