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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Plasma membrane calcium-transporting ATPase 3

UniprotKB/SwissProt ID: Q64568 (Q64568)

Gene Name: Atp2b3

Organism: Rattus norvegicus (Rat)

Function: ATP-driven Ca(2+) ion pump involved in the maintenance of basal intracellular Ca(2+) levels at the presynaptic terminals. Uses ATP as an energy source to transport cytosolic Ca(2+) ions across the plasma membrane to the extracellular compartment (PubMed:25014339, PubMed:9880546). May counter-transport protons, but the mechanism and the stoichiometry of this Ca(2+)/H(+) exchange remains to be established (PubMed:25014339, PubMed:9880546)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Presynaptic cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR022141 ATP_Ca_trans_C
IPR006068 ATPase_P-typ_cation-transptr_C
IPR004014 ATPase_P-typ_cation-transptr_N
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006408 P-type_ATPase_IIB
IPR001757 P_typ_ATPase
IPR044492 P_typ_ATPase_HD_dom

The S-nitrosylation sites of Q64568

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 461 DNNLVRHLDA C ETMGNATAIC   
2 471 CETMGNATAI C SDKTGTLTTN