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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Cytochrome P450 2C29

UniprotKB/SwissProt ID: Q64458 (Q64458)

Gene Name: Cyp2c29

Organism: Mus musculus (Mouse)

Function: A cytochrome P450 monooxygenase that selectively catalyzes the epoxidation of 14,15 double bond of (5Z,8Z,11Z,14Z)-eicosatetraenoic acid (arachidonate) forming 14,15-epoxyeicosatrienoic acid (14,15-EET) regioisomer. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH--hemoprotein reductase)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane. Microsome membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR008068 Cyt_P450_E_grp-I_CYP2B-like
IPR036396 Cyt_P450_sf
IPR050182 Cytochrome_P450_fam2

The S-nitrosylation sites of Q64458

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 151 IEDRVQEEAQ C LVEELRKTKG   
2 372 LPTSLPHAVT C DIKFRKYLIP   
3 435 FMPFSTGKRI C AGEGLARMEL