Protein Name:
ATP-binding cassette sub-family G member 1
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UniprotKB/SwissProt ID: Q64343 (Q64343)
Gene Name:
Abcg1
Organism: Mus musculus (Mouse)
Function: Catalyzes the efflux of phospholipids such as sphingomyelin, cholesterol and its oxygenated derivatives like 7beta-hydroxycholesterol and this transport is coupled to hydrolysis of ATP (PubMed:14668945). The lipid efflux is ALB-dependent. Is an active component of the macrophage lipid export complex. Could also be involved in intracellular lipid transport processes. The role in cellular lipid homeostasis may not be limited to macrophages. Prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell membrane
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Graphical Visualization of S-nitrosylation Sites:
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