UniprotKB/SwissProt ID: Q64018 (Q64018)
Gene Name:
Glra1
Organism: Mus musculus (Mouse)
Function: Subunit of heteromeric glycine-gated chloride channels (PubMed:16672662, PubMed:17114051, PubMed:24801766). Plays an important role in the down-regulation of neuronal excitability (PubMed:9145798). Contributes to the generation of inhibitory postsynaptic currents (PubMed:16672662, PubMed:17114051, PubMed:24801766). Channel activity is potentiated by ethanol. Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (PubMed:24801766)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Postsynaptic cell membrane. Synapse. Perikaryon. Cell projection, dendrite. Cell membrane
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