UniprotKB/SwissProt ID: Q63560 (Q63560)
Gene Name:
Map6
Organism: Rattus norvegicus (Rat)
Function: Involved in microtubule stabilization in many cell types, including neuronal cells (PubMed:11413126, PubMed:28521134, PubMed:3456161, PubMed:8700896, PubMed:9660871). Specifically has microtubule cold stabilizing activity (PubMed:3456161). Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B (By similarity). Regulates KIF5A-mediated axonal cargo transport (PubMed:28521134). Regulates axonal growth during neuron polarization (PubMed:28521134)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytoskeleton. Golgi apparatus. Cell projection, axon. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle membrane
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