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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Complement component receptor 1-like protein

UniprotKB/SwissProt ID: Q63135 (Q63135)

Gene Name: Cr1l

Organism: Rattus norvegicus (Rat)

Function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Seems to act as a costimulatory factor for T-cells. May play a crucial role in early embryonic development by maintaining fetomaternal tolerance

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR051277 SEZ6_CSMD_C4BPB_Regulators
IPR035976 Sushi/SCR/CCP_sf
IPR000436 Sushi_SCR_CCP_dom

The S-nitrosylation sites of Q63135

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 288 LNRWEPQLPS C FKVKSCGAFL