Protein Name:
Mitogen-activated protein kinase kinase kinase 1
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UniprotKB/SwissProt ID: Q62925 (Q62925)
Gene Name:
Map3k1
Organism: Rattus norvegicus (Rat)
Function: Component of a protein kinase signal transduction cascade (PubMed:11784851). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:11784851). May phosphorylate the MAPK8/JNK1 kinase (By similarity). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:11784851)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane
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Graphical Visualization of S-nitrosylation Sites:
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