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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Heterogeneous nuclear ribonucleoprotein M

UniprotKB/SwissProt ID: Q62826 (Q62826)

Gene Name: Hnrnpm

Organism: Rattus norvegicus (Rat)

Function: Pre-mRNA binding protein, binds avidly to poly(G) and poly(U) RNA homopolymers. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus matrix

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR024666 HnRNP_M_PY-NLS
IPR034990 hnRNPM_RRM3
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR050374 RRT5_SRSF_SR

The S-nitrosylation sites of Q62826

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 113 LMDAEGKSRG C AVVEFKMEES   
2 26 PKMEEESGAP C VPSGNGAPVP   
3 613 GHAPGVARKA C QIFVRNLPFD   
4 636 WKMLKDKFNE C GHVLYADIKM   
5 654 IKMENGKSKG C GVVKFESPEV