UniprotKB/SwissProt ID: Q62758 (Q62758)
Gene Name:
Htr4
Organism: Rattus norvegicus (Rat)
Function: G-protein coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:10220570, PubMed:7796807). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors (By similarity). HTR4 is coupled to G(s) G alpha proteins and mediates activation of adenylate cyclase activity (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Endosome membrane
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