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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Ras-related protein Rap-1b

UniprotKB/SwissProt ID: Q62636 (Q62636)

Gene Name: Rap1b

Organism: Rattus norvegicus (Rat)

Function: GTP-binding protein that possesses intrinsic GTPase activity. Contributes to the polarizing activity of KRIT1 and CDH5 in the establishment and maintenance of correct endothelial cell polarity and vascular lumen. Required for the localization of phosphorylated PRKCZ, PARD3 and TIAM1 to the cell junction. Plays a role in the establishment of basal endothelial barrier function (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane. Cytoplasm, cytosol. Cell junction

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR027417 P-loop_NTPase
IPR038851 Rap1
IPR005225 Small_GTP-bd
IPR001806 Small_GTPase
IPR020849 Small_GTPase_Ras-type

The S-nitrosylation sites of Q62636

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 141 GQNLARQWSN C AFLESSAKSK