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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: NADPH-dependent 3-keto-steroid reductase Hsd3b5

UniprotKB/SwissProt ID: Q61694 (Q61694)

Gene Name: Hsd3b5

Organism: Mus musculus (Mouse)

Function: Responsible for the reduction of the oxo group on the C-3 of 5alpha-androstane steroids. Catalyzes the conversion of dihydrotestosterone to its inactive form 5alpha-androstanediol, that does not bind androgen receptor/AR. Does not function as an isomerase

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane. Mitochondrion membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002225 3Beta_OHSteriod_DH/Estase
IPR050177 Lipid_A_modif_metabolic_enz
IPR036291 NAD(P)-bd_dom_sf

The S-nitrosylation sites of Q61694

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 183 LLKNGGTLHT C ALRLPFIYGE