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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Plastin-2

UniprotKB/SwissProt ID: Q61233 (Q61233)

Gene Name: Lcp1

Organism: Mus musculus (Mouse)

Function: Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton. Cell projection. Cell junction. Cell projection, ruffle membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR001589 Actinin_actin-bd_CS
IPR001715 CH_dom
IPR036872 CH_dom_sf
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
IPR039959 Fimbrin/Plastin

The S-nitrosylation sites of Q61233

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 101 RKAINKKEGI C AIGGTSEQSS  CCCCCCCHHH H HHHHHHHHCC  3.12%
2 140 INKALENDPD C RHVIPMNPNT  CCCCCCCHHH H HHHHHHHHCC  3.84% 24926564
3 164 FNAVGDGIVL C KMINLSVPDT  CCCCCCCHHH H HHHHHHHHCC  1.62%
4 31 VDTDGNGYIS C NELNDLFKAA  CCCCCCCHHH H HHHHHHHHCC  3.13% 24926564
19483679
5 336 REKDDIQRAE C MLQQAERLGC  CCCCCCCHHH H HHHHHHHHCC  3% 24926564
21278135
6 42 NELNDLFKAA C LPLPGYRVRE  CCCCCCCHHH H HHHHHHHHCC  4.86%
7 460 LGGNMKKLEN C NYAVDLGKNQ  CCCCCCCHHH H HHHHHHHHCC  2.77%