Protein Name:
Palmitoyltransferase ZDHHC20
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UniprotKB/SwissProt ID: Q5Y5T1 (Q5Y5T1)
Gene Name:
Zdhhc20
Organism: Mus musculus (Mouse)
Function: Palmitoyltransferase that could catalyze the addition of palmitate onto various protein substrates (PubMed:15603741). Catalyzes palmitoylation of Cys residues in the cytoplasmic C-terminus of EGFR, and modulates the duration of EGFR signaling by modulating palmitoylation-dependent EGFR internalization and degradation. Has a preference for acyl-CoA with C16 fatty acid chains. Can also utilize acyl-CoA with C14 and C18 fatty acid chains (By similarity). May palmitoylate CALHM1 subunit of gustatory voltage-gated ion channels and modulate channel gating and kinetics
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Golgi apparatus membrane. Cell membrane. Cytoplasm, perinuclear region. Endoplasmic reticulum membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane
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Graphical Visualization of S-nitrosylation Sites:
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