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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: ORC ubiquitin ligase 1

UniprotKB/SwissProt ID: Q5W0B1 (Q5W0B1)

Gene Name: OBI1

Organism: Homo sapiens (Human)

Function: E3 ubiquitin ligase essential for DNA replication origin activation during S phase (PubMed:31160578). Acts as a replication origin selector which selects the origins to be fired and catalyzes the multi-mono-ubiquitination of a subset of chromatin-bound ORC3 and ORC5 during S-phase (PubMed:31160578)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Chromosome

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR039209 OBI1
IPR035691 OBI1_RING-HC
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD

The S-nitrosylation sites of Q5W0B1

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 105 LHKEYEDEID C LQKEVEELKS