Protein Name:
Proteasome adapter and scaffold protein ECM29
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UniprotKB/SwissProt ID: Q5VYK3 (Q5VYK3)
Gene Name:
ECPAS
Organism: Homo sapiens (Human)
Function: Adapter/scaffolding protein that binds to the 26S proteasome, motor proteins and other compartment specific proteins. May couple the proteasome to different compartments including endosome, endoplasmic reticulum and centrosome. May play a role in ERAD and other enhanced proteolysis (PubMed:15496406). Promotes proteasome dissociation under oxidative stress (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum. Endoplasmic reticulum-Golgi intermediate compartment. Endosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Endosome, multivesicular body. Cytoplasmic vesicle
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5VYK3
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1070 |
GQGLSTYKEL C SLASDLSQPD |
CCHHHHHCCH H HHHHHHHHHH |
3.08% |
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| 2 |
1183 |
SNMWRVRESS C LALNDLLRGR |
CCHHHHHCCH H HHHHHHHHHH |
3.43% |
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| 3 |
1257 |
GQRTIAALLP C LLDKGMMSTV |
CCHHHHHCCH H HHHHHHHHHH |
6.26% |
19483679
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| 4 |
1364 |
SVLGELVPRL C ELIRSGVGLG |
CCHHHHHCCH H HHHHHHHHHH |
4.17% |
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| 5 |
1390 |
ASVIVSLTTQ C PQDLTPYSGK |
CCHHHHHCCH H HHHHHHHHHH |
2.84% |
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| 6 |
1503 |
ADEEKSEKEE C NLWTEVWQEN |
CCHHHHHCCH H HHHHHHHHHH |
5.49% |
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| 7 |
1594 |
GKEELLKAIA C VVTACSAELE |
CCHHHHHCCH H HHHHHHHHHH |
1.75% |
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| 8 |
1638 |
NVKYKIVAIS C AADILKATKE |
CCHHHHHCCH H HHHHHHHHHH |
2.71% |
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| 9 |
243 |
NPWTPEQLEQ C KLGIVKFIEA |
CCHHHHHCCH H HHHHHHHHHH |
2.61% |
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| 10 |
449 |
ALVQQLFEAL C KEEPETRLAI |
CCHHHHHCCH H HHHHHHHHHH |
7.22% |
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