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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Rho guanine nucleotide exchange factor 16

UniprotKB/SwissProt ID: Q5VV41 (Q5VV41)

Gene Name: ARHGEF16

Organism: Homo sapiens (Human)

Function: Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR035797 ARHGEF16/ARHGEF26_SH3
IPR035899 DBL_dom_sf
IPR000219 DH_dom
IPR047271 Ephexin-like
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR047270 PH_ephexin
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain