UniprotKB/SwissProt ID: Q5U4D8 (Q5U4D8)
Gene Name:
Slc5a6
Organism: Mus musculus (Mouse)
Function: Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide (PubMed:23104561). Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+):substrate is 2:1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake (By similarity). Required for biotin and pantothenate uptake in the intestine across the brush border membrane (PubMed:23104561). Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin (PubMed:27492331). Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Apical cell membrane
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