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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: A-kinase anchor protein 2

UniprotKB/SwissProt ID: Q5U301 (Q5U301)

Gene Name: Akap2

Organism: Rattus norvegicus (Rat)

Function: Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP. Binds to and modulates the structure of the actin cytoskeleton

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Apical cell membrane

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR029304 AKAP2_C

The S-nitrosylation sites of Q5U301

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 406 TQAAKEQKAL C VSESQSAGAG