dbSNO 2.0

Latest news:

Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

Protein Name: Prelamin-A/C

UniprotKB/SwissProt ID: Q5TCI8 (Q5TCI8)

Gene Name: LMNA

Organism: Homo sapiens (Human)

Function: Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus lamina. Nucleus matrix. Nucleus, nucleoplasm

Graphical Visualization of S-nitrosylation Sites:

InterPro ID	Domain Name
IPR018039	IF_conserved
IPR039008	IF_rod_dom
IPR001322	Lamin_tail_dom
IPR036415	Lamin_tail_dom_sf

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