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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Syntaxin-binding protein 5

UniprotKB/SwissProt ID: Q5T5C0 (Q5T5C0)

Gene Name: STXBP5

Organism: Homo sapiens (Human)

Function: Plays a regulatory role in calcium-dependent exocytosis and neurotransmitter release. Inhibits membrane fusion between transport vesicles and the plasma membrane. May modulate the assembly of trans-SNARE complexes between transport vesicles and the plasma membrane. Inhibits translocation of GLUT4 from intracellular vesicles to the plasma membrane. Competes with STXBP1 for STX1 binding (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cell membrane. Cytoplasmic vesicle membrane. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle. Synapse

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR000664 Lethal2_giant
IPR013905 Lgl_C_dom
IPR013577 LLGL2
IPR042855 V_SNARE_CC
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR036322 WD40_repeat_dom_sf
IPR001680 WD40_rpt

The S-nitrosylation sites of Q5T5C0

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 697 KSRQPSGAGL C DISEGTVVPE   
2 933 AKVISLPTQN C AYKQNITETS