Protein Name:
E3 ubiquitin-protein ligase HECTD3
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UniprotKB/SwissProt ID: Q5T447 (Q5T447)
Gene Name:
HECTD3
Organism: Homo sapiens (Human)
Function: E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, perinuclear region
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5T447
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
556 |
DSLADMSEEL C PSSADTPVPL |
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| 2 |
823 |
TTDALPESST C SSTLFLPHYA |
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