Protein Name:
Zinc finger CCCH domain-containing protein 13
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UniprotKB/SwissProt ID: Q5T200 (Q5T200)
Gene Name:
ZC3H13
Organism: Homo sapiens (Human)
Function: Associated component of the WMM complex, a complex that mediates N6-methyladenosine (m6A) methylation of RNAs, a modification that plays a role in the efficiency of mRNA splicing and RNA processing (PubMed:29507755). Acts as a key regulator of m6A methylation by promoting m6A methylation of mRNAs at the 3'-UTR (By similarity). Controls embryonic stem cells (ESCs) pluripotency via its role in m6A methylation (By similarity). In the WMM complex, anchors component of the MACOM subcomplex in the nucleus (By similarity). Also required for bridging WTAP to the RNA-binding component RBM15 (RBM15 or RBM15B) (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus speckle. Nucleus, nucleoplasm
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5T200
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1666 |
LSQSSIQQEL C VS-------- |
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| 2 |
51 |
QCRNWLKTGN C LYGNTCRFVH |
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