Protein Name:
Acyl-coenzyme A thioesterase THEM4
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UniprotKB/SwissProt ID: Q5T1C6 (Q5T1C6)
Gene Name:
THEM4
Organism: Homo sapiens (Human)
Function: Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays a role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane. Cell projection, ruffle membrane. Cytoplasm. Mitochondrion. Mitochondrion inner membrane. Mitochondrion intermembrane space
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5T1C6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
46 |
FSSEEVILKD C SVPNPSWNKD |
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