Protein Name:
Acetyl-CoA carboxylase 1
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UniprotKB/SwissProt ID: Q5SWU9 (Q5SWU9)
Gene Name:
Acaca
Organism: Mus musculus (Mouse)
Function: Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5SWU9
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1768 |
KRVSALNSVH C EHVEDEGESR |
CCCCCHHHHH E ECCCCCCEEE |
3.47% |
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| 2 |
812 |
KRPGAALDPG C VIAKMQLDNP |
CCCCCHHHHH E ECCCCCCEEE |
2.14% |
22178444
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