Protein Name:
Dapper homolog 2
|
UniprotKB/SwissProt ID: Q5SW24 (Q5SW24)
Gene Name:
DACT2
Organism: Homo sapiens (Human)
Function: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization:
|
|
|
Graphical Visualization of S-nitrosylation Sites:
|
|
