Protein Name:
Cytoplasmic FMR1-interacting protein 2
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UniprotKB/SwissProt ID: Q5SQX6 (Q5SQX6)
Gene Name:
Cyfip2
Organism: Mus musculus (Mouse)
Function: Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). Involved in T-cell adhesion and p53-dependent induction of apoptosis (By similarity). Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Synapse, synaptosome
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5SQX6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1253 |
PPIHQSLATT C ---------- |
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| 2 |
98 |
SCSRAIPQVK C NEQPNRVEIY |
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