Protein Name:
Protein flightless-1 homolog
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UniprotKB/SwissProt ID: Q5RKI5 (Q5RKI5)
Gene Name:
Flii
Organism: Rattus norvegicus (Rat)
Function: Is a regulator of actin polymerization, required for proper myofibril organization and regulation of the length of sarcomeric thin filaments. It also plays a role in the assembly of cardiomyocyte cell adhesion complexes. Regulates cytoskeletal rearrangements involved in cytokinesis and cell migration, by inhibiting Rac1-dependent paxillin phosphorylation. May play a role as coactivator in transcriptional activation by hormone-activated nuclear receptors (NR) and acts in cooperation with NCOA2 and CARM1. Involved in estrogen hormone signaling
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, focal adhesion. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5RKI5
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
1225 |
QVEIKLSLKA C QVYIQHTRSK |
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| 2 |
241 |
SCNDLTRVPE C LYTLPNLHRL |
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| 3 |
289 |
NQLTSLPSAI C KLTKLKKLYL |
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| 4 |
46 |
RWLKLNRTGL C YLPEELAALQ |
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| 5 |
560 |
GGEATLDKKA C SAIHAVNLRN |
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| 6 |
576 |
VNLRNYLGAE C RTAREEMGDE |
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