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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Protein OS-9

UniprotKB/SwissProt ID: Q5RKH6 (Q5RKH6)

Gene Name: Os9

Organism: Rattus norvegicus (Rat)

Function: Lectin component of the HRD1 complex, which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). Specifically recognizes and binds improperly folded glycoproteins as well as hyperglycosylated proteins, retain them in the ER, and transfers them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4 as well as hyperglycosylated HSP90B1

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum lumen

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR009011 Man6P_isomerase_rcpt-bd_dom_sf
IPR044865 MRH_dom
IPR045149 OS-9-like
IPR012913 OS9-like_dom

The S-nitrosylation sites of Q5RKH6

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 123 KTKDWWTYEF C YGRHIQQYHM