Protein Name:
Deoxynucleotidyltransferase terminal-interacting protein 2
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UniprotKB/SwissProt ID: Q5QJE6 (Q5QJE6)
Gene Name:
DNTTIP2
Organism: Homo sapiens (Human)
Function: Regulates the transcriptional activity of DNTT and ESR1. May function as a chromatin remodeling protein (PubMed:12786946, PubMed:15047147). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Nucleus, nucleolus
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5QJE6
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
116 |
VTRRRQILIA C SPVSSVRKKP |
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| 2 |
484 |
SLSGDTGSLS C DNALFVIDTT |
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| 3 |
618 |
VITPDFEKNH C VPPYSESKYQ |
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