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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

UniprotKB/SwissProt ID: Q5PPL3 (Q5PPL3)

Gene Name: Nsdhl

Organism: Rattus norvegicus (Rat)

Function: Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis. Also plays a role in the regulation of the endocytic trafficking of EGFR

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Endoplasmic reticulum membrane. Lipid droplet

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR002225 3Beta_OHSteriod_DH/Estase
IPR050177 Lipid_A_modif_metabolic_enz
IPR036291 NAD(P)-bd_dom_sf

The S-nitrosylation sites of Q5PPL3

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 329 ALAGTFHYYS C EKAKKLIGYR