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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: Serine/threonine-protein kinase DCLK2

UniprotKB/SwissProt ID: Q5MPA9 (Q5MPA9)

Gene Name: Dclk2

Organism: Rattus norvegicus (Rat)

Function: Protein kinase with a significantly reduced Ca(2+)+/CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity)

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm, cytoskeleton

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR003533 Doublecortin_dom
IPR036572 Doublecortin_dom_sf
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS

The S-nitrosylation sites of Q5MPA9

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 287 QDDFVLDHSE C RVLKSSYSRA   
2 539 RDIKPENLLV C EYPDGTKSLK