Protein Name:
Transmembrane emp24 domain-containing protein 9
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UniprotKB/SwissProt ID: Q5I0E7 (Q5I0E7)
Gene Name:
Tmed9
Organism: Rattus norvegicus (Rat)
Function: Appears to be involved in vesicular protein trafficking, mainly in the early secretory pathway. In COPI vesicle-mediated retrograde transport involved in the coatomer recruitment to membranes of the early secretory pathway. Increases coatomer-dependent activity of ARFGAP2. Thought to play a crucial role in the specific retention of p24 complexes in cis-Golgi membranes; specifically contributes to the coupled localization of TMED2 and TMED10 in the cis-Golgi network. May be involved in organization of intracellular membranes, such as of the ER-Golgi intermediate compartment and the Golgi apparatus. Involved in ER localization of PTPN2 (By similarity)
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Endoplasmic reticulum membrane. Golgi apparatus, cis-Golgi network membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus, trans-Golgi network membrane
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q5I0E7
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
49 |
YFHIGETEKK C FIEEIPDETM |
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