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Sep. 10, 2014:
A total of 174 experimentally verified S-nitrosylation sites on 94 S-nitrosylated proteins from individualized human colorectal cancer tissues using a label-free quantitation strategy.

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Protein Name: TATA box-binding protein-associated factor RNA polymerase I subunit B

UniprotKB/SwissProt ID: Q53T94 (Q53T94)

Gene Name: TAF1B

Organism: Homo sapiens (Human)

Function: Component of RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. Binds rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex and, possibly, directly through its interaction with RRN3

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus, nucleolus

Graphical Visualization of S-nitrosylation Sites:
InterPro ID Domain Name
IPR048538 Rrn7_cyclin_C
IPR048540 Rrn7_cyclin_N
IPR033599 TAF1B/Rrn7
IPR021752 TF_Rrn7_Zf

The S-nitrosylation sites of Q53T94

No. Position S-nitrosylated Peptide Secondary Structure of S-nitrosylated Peptide Solvent Accessibility of nitrosylated Site PubMed ID
1 189 SKASQSETSV C SGSLDGVEYS