Protein Name:
FLYWCH-type zinc finger-containing protein 1
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UniprotKB/SwissProt ID: Q4VC44 (Q4VC44)
Gene Name:
FLYWCH1
Organism: Homo sapiens (Human)
Function: Transcription cofactor (PubMed:30097457). Negatively regulates transcription activation by catenin beta-1 CTNNB1, perhaps acting by competing with TCF4 for CTNNB1 binding (PubMed:30097457). May play a role in DNA-damage response signaling (PubMed:33924684). Binds specifically to DNA sequences at peri-centromeric chromatin loci
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Chromosome, centromere
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Graphical Visualization of S-nitrosylation Sites:
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The S-nitrosylation sites of Q4VC44
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| No. |
Position |
S-nitrosylated Peptide |
Secondary Structure of S-nitrosylated Peptide |
Solvent Accessibility of nitrosylated Site |
PubMed ID |
| 1 |
224 |
EPLEGVGPWQ C PEEPEPTPGL |
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| 2 |
304 |
KAVGDKVYWT C RDHALHGCRS |
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| 3 |
452 |
KAAGEKVYWT C RDQARMGCRS |
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| 4 |
540 |
KAAGEKVYWT C RDQARMGCRS |
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